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MITOCHONDRIAL FUNCTION

Humanin

Humanin is a mitochondrial function peptide used in evidence-based, physician-supervised protocols. Use for neuroprotection, Alzheimer's prevention/treatment, mitochondrial dysfunction, or metabolic optimization.

What is Humanin?

Mitochondria-derived peptide (MDP) encoded by mitochondrial 16S rRNA. Neuroprotective — blocks amyloid-beta toxicity, protects against apoptosis, preserves mitochondrial membrane potential. Also reduces insulin resistance and preserves metabolic function. Circulates as endogenous hormone declining with age.

Uses & clinical decision logic

Use for neuroprotection, Alzheimer's prevention/treatment, mitochondrial dysfunction, or metabolic optimization. 4-6 week cycles.

Humanin dosage & administration

Vial sizeBAC waterDosing rangeUnits / doseFrequencyRoute
5mg2mL5-20mg200-800 units3x/week or QODSubQ
10mg2mL5-20mg100-400 units3x/week or QODSubQ

Safety & contraindications

Limited clinical data in humans — use conservatively.

Stacking & combinations

Pairs with SS-31 (inner mitochondrial membrane) and MOTS-c (nuclear gene expression); compatible with NAD+.

Related peptides

Frequently asked questions

What is Humanin used for?

Use for neuroprotection, Alzheimer's prevention/treatment, mitochondrial dysfunction, or metabolic optimization. 4-6 week cycles.

What is the typical Humanin dosage?

Common dosing ranges from 5-20mg (3x/week or QOD, SubQ). Exact dosing is individualized and set by a licensed physician.

How is Humanin administered?

Humanin is typically administered via SubQ.

What are the contraindications for Humanin?

Limited clinical data in humans — use conservatively.

Considering Humanin?

Build a physician-supervised protocol around your goal — no gatekeeping, real doctors, 503A compounding pharmacies.

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This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.