PepSight
IMMUNITY/NEUROIMMUNE

VIP (Vasoactive Intestinal Peptide)

VIP (Vasoactive Intestinal Peptide) is a immunity/neuroimmune peptide used in evidence-based, physician-supervised protocols. Use for CIRS (Chronic Inflammatory Response Syndrome), dysautonomia, MCAS, pulmonary fibrosis, or post-COVID inflammatory syndromes.

What is VIP (Vasoactive Intestinal Peptide)?

Vasoactive Intestinal Peptide — 28-AA neuropeptide/immune modulator. Binds VPAC1/VPAC2 receptors; potently anti-inflammatory (suppresses TNF-alpha, IL-6, IL-12); regulates autonomic nervous system; bronchodilatory; neuroprotective. Intranasal delivery targets CNS and pulmonary mucosa directly.

Uses & clinical decision logic

Use for CIRS (Chronic Inflammatory Response Syndrome), dysautonomia, MCAS, pulmonary fibrosis, or post-COVID inflammatory syndromes. Start low (50mcg) and titrate — some patients are very sensitive. SubQ: 50-200mcg.

VIP (Vasoactive Intestinal Peptide) dosage & administration

Vial sizeBAC waterDosing rangeUnits / doseFrequencyRoute
5mg2mL50-100mcg2-4 units1-4x dailyIntranasal/SubQ
10mg4mL50-200mcg2-8 units1-4x dailyIntranasal/SubQ

Safety & contraindications

Start at low dose — hypotension and flushing possible. Contraindicated in active GI bleeding.

Stacking & combinations

Compatible with BPC-157 and KPV for gut-neuroimmune stack.

Related peptides

Frequently asked questions

What is VIP (Vasoactive Intestinal Peptide) used for?

Use for CIRS (Chronic Inflammatory Response Syndrome), dysautonomia, MCAS, pulmonary fibrosis, or post-COVID inflammatory syndromes. Start low (50mcg) and titrate — some patients are very sensitive. SubQ: 50-200mcg.

What is the typical VIP (Vasoactive Intestinal Peptide) dosage?

Common dosing ranges from 50-100mcg (1-4x daily, Intranasal/SubQ). Exact dosing is individualized and set by a licensed physician.

How is VIP (Vasoactive Intestinal Peptide) administered?

VIP (Vasoactive Intestinal Peptide) is typically administered via Intranasal/SubQ.

What are the contraindications for VIP (Vasoactive Intestinal Peptide)?

Start at low dose — hypotension and flushing possible. Contraindicated in active GI bleeding.

Considering VIP (Vasoactive Intestinal Peptide)?

Build a physician-supervised protocol around your goal — no gatekeeping, real doctors, 503A compounding pharmacies.

Build your protocol →

This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.