Sermorelin
Sermorelin is a growth hormone releasing peptide used in evidence-based, physician-supervised protocols. Use for patients preferring a more natural GHRH peptide vs.
What is Sermorelin?
29-AA GHRH analogue (first 29 AA of native GHRH). Stimulates GHRH-R on somatotrophs for GH pulse. Shortest GHRH analogue — more physiological than CJC. Half-life ~12 min. Administer fasted 2 hrs before first meal or at bedtime.
Uses & clinical decision logic
Use for patients preferring a more natural GHRH peptide vs. synthetic CJC analogues. Also used for GH deficiency assessment (stimulation test).
Sermorelin dosage & administration
| Vial size | BAC water | Dosing range | Units / dose | Frequency | Route |
|---|---|---|---|---|---|
| 5mg | 1mL | 500mcg-2mg | 10-40 units | 5 days on / 2 off | SubQ |
| 10mg | 2mL | 500mcg-2mg | 10-40 units | 5 days on / 2 off | SubQ |
Safety & contraindications
Same class — active cancer contraindication. Monitor IGF-1.
Stacking & combinations
Pair with Ipamorelin or GHRP-2 for dual GHRH+GHRP synergy.
Related peptides
Frequently asked questions
What is Sermorelin used for?
Use for patients preferring a more natural GHRH peptide vs. synthetic CJC analogues. Also used for GH deficiency assessment (stimulation test).
What is the typical Sermorelin dosage?
Common dosing ranges from 500mcg-2mg (5 days on / 2 off, SubQ). Exact dosing is individualized and set by a licensed physician.
How is Sermorelin administered?
Sermorelin is typically administered via SubQ.
What are the contraindications for Sermorelin?
Same class — active cancer contraindication. Monitor IGF-1.
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Build your protocol →This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.