PepSight
BRAIN + MOOD

Semax

Semax is a brain + mood peptide used in evidence-based, physician-supervised protocols. Use for cognitive enhancement, attention, neuroplasticity, neurological injury recovery, and as part of brain optimization stack.

What is Semax?

Synthetic ACTH(4-7) analogue — Pro-Gly-Pro extension. Potently upregulates BDNF, NGF, and VEGF in hippocampus. Improves cerebral blood flow, neuroplasticity, attention, and memory. No endocrine effects (does not activate HPA axis).

Uses & clinical decision logic

Use for cognitive enhancement, attention, neuroplasticity, neurological injury recovery, and as part of brain optimization stack.

Semax dosage & administration

Vial sizeBAC waterDosing rangeUnits / doseFrequencyRoute
5mg1mL500mcg-1mg10-20 unitsDailySubQ
10mg2mL500mcg-1mg10-20 unitsDailySubQ

Safety & contraindications

Stimulating — avoid in PM. Can cause mild headache at initiation.

Stacking & combinations

Classic pairing with Selank (cognitive + anxiolytic balance). Synergistic with Dihexa, NAD+, Adamax, Cerebrolysin.

Related peptides

Frequently asked questions

What is Semax used for?

Use for cognitive enhancement, attention, neuroplasticity, neurological injury recovery, and as part of brain optimization stack.

What is the typical Semax dosage?

Common dosing ranges from 500mcg-1mg (Daily, SubQ). Exact dosing is individualized and set by a licensed physician.

How is Semax administered?

Semax is typically administered via SubQ.

What are the contraindications for Semax?

Stimulating — avoid in PM. Can cause mild headache at initiation.

Considering Semax?

Build a physician-supervised protocol around your goal — no gatekeeping, real doctors, 503A compounding pharmacies.

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This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.