PT-141 (Bremelanotide)
PT-141 (Bremelanotide) is a libido/ed peptide used in evidence-based, physician-supervised protocols. Use for hypoactive sexual desire disorder, ED unresponsive to PDE5 inhibitors, or libido enhancement.
What is PT-141 (Bremelanotide)?
Melanocortin receptor agonist (MC3R/MC4R activation) in CNS — directly stimulates sexual arousal pathways in hypothalamus independent of vascular mechanism. FDA-approved for HSDD in premenopausal women. Works in both men and women. Must administer 2 hrs before activity. Max 20 units per dose.
Uses & clinical decision logic
Use for hypoactive sexual desire disorder, ED unresponsive to PDE5 inhibitors, or libido enhancement.
PT-141 (Bremelanotide) dosage & administration
| Vial size | BAC water | Dosing range | Units / dose | Frequency | Route |
|---|---|---|---|---|---|
| 5mg | 1mL | 500mcg-1mg | 10-20 units | 2 hrs before activity PRN | SubQ |
| 10mg | 2mL | 500mcg-1mg | 10-20 units | 2 hrs before activity PRN | SubQ |
Safety & contraindications
Nausea is common side effect — start at 500mcg. Can cause transient blood pressure increase — caution in hypertension. Do not exceed 20 units.
Stacking & combinations
Can complement with Kisspeptin for hormonal libido enhancement; compatible with testosterone therapy.
Related peptides
Frequently asked questions
What is PT-141 (Bremelanotide) used for?
Use for hypoactive sexual desire disorder, ED unresponsive to PDE5 inhibitors, or libido enhancement.
What is the typical PT-141 (Bremelanotide) dosage?
Common dosing ranges from 500mcg-1mg (2 hrs before activity PRN, SubQ). Exact dosing is individualized and set by a licensed physician.
How is PT-141 (Bremelanotide) administered?
PT-141 (Bremelanotide) is typically administered via SubQ.
What are the contraindications for PT-141 (Bremelanotide)?
Nausea is common side effect — start at 500mcg. Can cause transient blood pressure increase — caution in hypertension. Do not exceed 20 units.
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Build your protocol →This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.