PepSight
BRAIN + MOOD

NAD+

NAD+ is a brain + mood peptide used in evidence-based, physician-supervised protocols. Use for cognitive decline, energy optimization, anti-aging, addiction recovery, and post-NAD+ oral support.

What is NAD+?

Nicotinamide adenine dinucleotide — essential coenzyme for >500 enzymatic reactions. Fuels sirtuins (SIRT1-7), PARP repair enzymes, and mitochondrial complex I. Declines ~50% by age 60. Restores cellular energy metabolism, DNA repair capacity, and neurological function. IM injection for systemic use. Single dose max 250mg IM.

Uses & clinical decision logic

Use for cognitive decline, energy optimization, anti-aging, addiction recovery, and post-NAD+ oral support.

NAD+ dosage & administration

Vial sizeBAC waterDosing rangeUnits / doseFrequencyRoute
100mg2mL50-100mg100-200 unitsDaily or 2x/weekIM
500mg2mL50-150mg20-60 unitsDaily or 2x/weekIM
1,000mg2mL100-250mg20-50 unitsDaily or 2x/weekIM/IV

Safety & contraindications

IV preferred for addiction recovery — use 500-1000mg over 2-4 hrs with medical supervision.

Stacking & combinations

Synergizes with SS-31 (mitochondrial targeting) and MOTS-c; pairs with Semax/Selank for neuro stack.

Related peptides

Frequently asked questions

What is NAD+ used for?

Use for cognitive decline, energy optimization, anti-aging, addiction recovery, and post-NAD+ oral support.

What is the typical NAD+ dosage?

Common dosing ranges from 50-100mg (Daily or 2x/week, IM). Exact dosing is individualized and set by a licensed physician.

How is NAD+ administered?

NAD+ is typically administered via IM.

What are the contraindications for NAD+?

IV preferred for addiction recovery — use 500-1000mg over 2-4 hrs with medical supervision.

Considering NAD+?

Build a physician-supervised protocol around your goal — no gatekeeping, real doctors, 503A compounding pharmacies.

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This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.