PepSight
GROWTH FACTOR

IGF-1 LR3

IGF-1 LR3 is a growth factor peptide used in evidence-based, physician-supervised protocols. Use for muscle development, recovery, body recomposition.

What is IGF-1 LR3?

Long-chain IGF-1 analogue with Arg3 substitution and 13-AA N-terminal extension. Reduced IGFBP binding (3-4x longer half-life than native IGF-1). Binds IGF-1R to promote muscle protein synthesis, satellite cell activation, and systemic anabolic signaling. Lower dose range option. Administer after meal or before gym session.

Uses & clinical decision logic

Use for muscle development, recovery, body recomposition. Lower dose vial for conservative protocols or new users.

IGF-1 LR3 dosage & administration

Vial sizeBAC waterDosing rangeUnits / doseFrequencyRoute
0.1mg1mL20-50mcg20-50 units5 days on / 2 offIM
1mg1mL100-200mcg10-20 units5 days on / 2 offIM

Safety & contraindications

May cause hypoglycemia — inject with or after food. Avoid in insulin-dependent diabetics without glucose monitoring. Monitor for acromegaly symptoms at high doses.

Stacking & combinations

Combines with GH peptides for GH + IGF-1 synergy; pairs with Follistatin 344 and MGF for muscle development protocol.

Related peptides

Frequently asked questions

What is IGF-1 LR3 used for?

Use for muscle development, recovery, body recomposition. Lower dose vial for conservative protocols or new users.

What is the typical IGF-1 LR3 dosage?

Common dosing ranges from 20-50mcg (5 days on / 2 off, IM). Exact dosing is individualized and set by a licensed physician.

How is IGF-1 LR3 administered?

IGF-1 LR3 is typically administered via IM.

What are the contraindications for IGF-1 LR3?

May cause hypoglycemia — inject with or after food. Avoid in insulin-dependent diabetics without glucose monitoring. Monitor for acromegaly symptoms at high doses.

Considering IGF-1 LR3?

Build a physician-supervised protocol around your goal — no gatekeeping, real doctors, 503A compounding pharmacies.

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This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.