PepSight
LONGEVITY

Epithalon

Epithalon is a longevity peptide used in evidence-based, physician-supervised protocols. Core longevity peptide — use for anti-aging, telomere protection, circadian normalization, and melatonin optimization.

What is Epithalon?

Tetrapeptide (Ala-Glu-Asp-Gly) from pineal gland. Activates telomerase, lengthens telomeres in somatic cells, stimulates melatonin production, normalizes cortisol circadian rhythm. Only known peptide with direct telomerase activation. 2-3 cycles/year recommended.

Uses & clinical decision logic

Core longevity peptide — use for anti-aging, telomere protection, circadian normalization, and melatonin optimization. Protocol: 10mg daily x 20 days = 1 cycle.

Epithalon dosage & administration

Vial sizeBAC waterDosing rangeUnits / doseFrequencyRoute
10mg1mL10mg100 units20 bottle cycle (daily x 20 days)SubQ
50mg2mL10-20mg40-80 units4 bottle cycle over 10-20 daysSubQ

Safety & contraindications

Minimal reported side effects — well-tolerated in trials.

Stacking & combinations

Pairs with Pinealon (circadian), MOTS-c and SS-31 (mitochondrial), Thymalin (immune) for comprehensive longevity stack.

Related peptides

Frequently asked questions

What is Epithalon used for?

Core longevity peptide — use for anti-aging, telomere protection, circadian normalization, and melatonin optimization. Protocol: 10mg daily x 20 days = 1 cycle.

What is the typical Epithalon dosage?

Common dosing ranges from 10mg (20 bottle cycle (daily x 20 days), SubQ). Exact dosing is individualized and set by a licensed physician.

How is Epithalon administered?

Epithalon is typically administered via SubQ.

What are the contraindications for Epithalon?

Minimal reported side effects — well-tolerated in trials.

Considering Epithalon?

Build a physician-supervised protocol around your goal — no gatekeeping, real doctors, 503A compounding pharmacies.

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This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.