PepSight
BRAIN + MOOD

Dihexa

Dihexa is a brain + mood peptide used in evidence-based, physician-supervised protocols. Use for cognitive decline, memory enhancement, neuroplasticity, or post-injury synaptogenesis.

What is Dihexa?

HGF/c-Met modulator (hepatocyte growth factor receptor agonist). Potently induces synaptogenesis and dendritic spine formation. ~10 million times more potent than BDNF at synaptic formation. Avoid evening dosing (stimulating). Start low and titrate slowly — effects are cumulative.

Uses & clinical decision logic

Use for cognitive decline, memory enhancement, neuroplasticity, or post-injury synaptogenesis. Morning only.

Dihexa dosage & administration

Vial sizeBAC waterDosing rangeUnits / doseFrequencyRoute
5mg1mL1-3mg20-60 unitsDaily (morning)SubQ
10mg2mL1-5mg20-100 unitsDaily (morning)SubQ

Safety & contraindications

Powerful effect — start at 1mg; too aggressive titration causes overstimulation. Long-term data limited.

Stacking & combinations

Synergistic with Cerebrolysin and Semax for neurotrophic amplification; pair with PE-22-28 for antidepressant + cognitive synergy.

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Frequently asked questions

What is Dihexa used for?

Use for cognitive decline, memory enhancement, neuroplasticity, or post-injury synaptogenesis. Morning only.

What is the typical Dihexa dosage?

Common dosing ranges from 1-3mg (Daily (morning), SubQ). Exact dosing is individualized and set by a licensed physician.

How is Dihexa administered?

Dihexa is typically administered via SubQ.

What are the contraindications for Dihexa?

Powerful effect — start at 1mg; too aggressive titration causes overstimulation. Long-term data limited.

Considering Dihexa?

Build a physician-supervised protocol around your goal — no gatekeeping, real doctors, 503A compounding pharmacies.

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This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.