Cagrilintide
Cagrilintide is a weight management peptide used in evidence-based, physician-supervised protocols. Add to GLP-1 therapy (CagriSema combination) to reduce GLP-1 required dose while amplifying weight loss.
What is Cagrilintide?
Long-acting amylin analogue. Acts on CNS amylin receptors (area postrema) to reduce food intake, slow gastric emptying, and suppress glucagon. Complementary to GLP-1 — different receptor, additive satiety signaling.
Uses & clinical decision logic
Add to GLP-1 therapy (CagriSema combination) to reduce GLP-1 required dose while amplifying weight loss. Used clinically in trials achieving >20% weight reduction in combination.
Cagrilintide dosage & administration
| Vial size | BAC water | Dosing range | Units / dose | Frequency | Route |
|---|---|---|---|---|---|
| 10mg | 2mL | 300mcg-4.5mg | 6-90 units | 1x/week | SubQ |
Safety & contraindications
Nausea at initiation — titrate from low dose.
Stacking & combinations
Designed to pair with semaglutide; compatible with tirzepatide at adjusted doses.
Related peptides
Frequently asked questions
What is Cagrilintide used for?
Add to GLP-1 therapy (CagriSema combination) to reduce GLP-1 required dose while amplifying weight loss. Used clinically in trials achieving >20% weight reduction in combination.
What is the typical Cagrilintide dosage?
Common dosing ranges from 300mcg-4.5mg (1x/week, SubQ). Exact dosing is individualized and set by a licensed physician.
How is Cagrilintide administered?
Cagrilintide is typically administered via SubQ.
What are the contraindications for Cagrilintide?
Nausea at initiation — titrate from low dose.
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Build your protocol →This page is for educational purposes only and is not medical advice. Peptide therapies described here are provided under physician supervision through 503A compounding pharmacies. Many peptides are not FDA-approved for the uses described. Do not start, stop, or change any protocol without consulting a licensed physician.